Certain COVID-19 vaccine candidates could increase susceptibility to HIV, warns a group of researchers who in 2007 learned that an experimental HIV vaccine had raised in some people the risk for infection with the AIDS virus.
“It's disappointing that none of the four (treatments) have come out and shown a difference in mortality, but it does show why you need big trials,” says Jeremy Farrar, director of the Wellcome Trust, a U.K. research-charity.
When prominent scientists pushed back against recommending face masks to help control the spread of COVID-19, and the U.K. government followed their lead, Trisha Greenhalgh was furious.
When Deborah Birx was named coordinator of the White House Coronavirus Task Force in February, she was widely praised as a voice of data-driven reason. But some of her actions have undermined the effectiveness of the CDC, according to a Science investigation.
Success in the push to find a COVID-19 vaccine at record-breaking speed could result in the first vaccine to cross the finish line might be only marginally effective.
A study of some of the sickest COVID-19 patients, such as those placed on ventilators, has identified gene variants that put people at greater risk of severe disease.
CRISPR gene-editing technology was used in developing the new coronavirus test. “It looks like they have a really rock-solid test,” says molecular biologist Max Wilson. “It’s really quite elegant.”
Systematic reviews typically take one or two years to complete. In the push for quick answers, have pandemic-related evaluations of studies sacrificed thoroughness and rigor?
“We should take a cold, hard look at all of the data and ask ourselves, ‘What appears to work best?’” says Nancy Haigwood, who directs the Oregon National Primate Research Center and is a key advocate for the comparative monkey study.
“Despite a lot of the political noise, the science is going well,” said Francis Collins, director of the National Institutes of Health (NIH).
Sweden's government never ordered a “shutdown" in response to the coronavirus pandemic. Its approach, out of step with much of the world, sparked debate on whether the strategy was brilliant or irresponsible.
In an hourlong, socially distanced interview with Science, Dr. Anthony Fauci discussed everything from his relationship with President Donald Trump to COVID-19 vaccines being tested.